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Whole Genome Screening Pathway

The Practicalities – How is it done?

The journey begins with a full Medical at 90 Sloane Street or an accepted approved GP partner centre which fulfils our protocol. This includes a full history of current and past illnesses, together with family history and any medication taken. You will undergo a detailed examination, a blood screen, ECG, echocardiogram as well as an abdominal and pelvic ultrasound. All these tests are non-invasive and have no radiation.

Colonoscopy and CT coronary angiogram screening will be discussed individually and is not needed in all cases.

When you apply for whole genome screening at The London Genetics Centre you will be emailed an information pack.

This includes a more detailed explanation of the pathway and a family history questionnaire as well as Consent forms to fill in. You can then email the family history questionnaire back and book your appointment/Medical. At the Medical you bring the consent forms you have read and sign only when you are at the practice after the Pre-screen counselling. This is a 30 minute appointment immediately after your full medical, and following which your whole genome sequencing test can be sent off.

Where and Who will be conducting various aspects of the different tests?

All tests will be done at The London Genetics Centre. Shortly, we plan to extend this initiative so that other partnership practices can do the Medical part for their own patients.

You will have your Medical with a GP and the pre-counselling by a genetically trained doctor (which may also be your GP if they have undergone specific training for this). The heart tests, ECG and Echocardiogram will be done by our cardiac technician. The ultrasound is done by a specialist radiologist. You receive your genome result with a Consultant Geneticist at The London Genetics Centre.

We are doing whole genome sequencing as a part of best medical care with a full medical assessment.

We have developed the “Next Generation Screening”.